Effect of Aloe vera on cowper's gland of Rattus norvegicus Dhurvey Varsha, Karim Firdos1,*, Urkude Rashmi2 Department of Zoology, RTM Nagpur University, Nagpur 1Department of Zoology, Kamla Nehru Mahavidyalaya, Nagpur 2Department of Chemistry, Shivaji Science College, Nagpur *Corresponding author: varshadhurvey@yahoo.com
Online published on 12 July, 2024. Abstract Aloe vera plant belongs to Liliaceae family, and is perennial, xerophytic, shrubby, succulent plant. In the current investigation effect of Aloe vera on body weight, organ weight, biochemistry and histology of Cowper's gland in male wistar rats was studied. In this experiment 12 mature adult male rats were. divided into 2 groups. Group I was control whereas group II was experimental. The rats from experimental group were daily administered 25 mg/kg body weight (BW) Aloe vera orally for 45 days, while those from group I received saline solution. After completion of the treatment rats were anaesthetized by ether, Cowper's gland was excised, weighed and processed for microbiological and biochemical estimations. The paraffin sections were stained with hematoxylin and eosin for histopathological observation. The results revealed significant drop in body weight, organ weight, total proteins and sialic acid concentration of experimental rat. Histopathological changes included reduction in the size of alveoli and decline in the secretary activity of acini, resulting into empty tubules. The secretory epithelium showed reduction in height, uneven arrangement and aggregation of nuclei. It is was concluded that consumption of Aloe vera has damaging effect on Cowper's gland which may affect male fertility. Top Keywords Aloe vera, Cowper's gland, Alveoli, Histology, Fertility. Top |