Anti-ulcer activity of silver nanoparticles in Albino rats Ghoshal Kalpana P.*, Ghatole Ajay M.1 Department of Botany, Dhote Bandhu Science College, Gondia, India 1Department of Chemistry, J. M. Patel Science College, Bhandara, India *E-mail: kalpanaghoshal71@gmail.com
Online published on 17 October, 2024. Abstract The anti-ulcer activity of silver nanoparticles prepared with Butea monosperma (SNBM) was studied in Swiss albino rats. The effects of the SNBM at the doses of 300 and 550 mg/kg per were compared with famotidine (35 mg/kg b.w.). The results revealed substantial protection against ulcers generated by indomethacin and histamine. In addition, SNBM drastically lowered lipid peroxide level and restored glutathione level. In conclusion SNBM demonstrated anti-ulcer activity by enhancing gastric mucosa's antioxidant capacity and minimizing mucosal damage. Top Keywords Silver Nanoparticles, Butea monosperma, Anti-Ulcer Activity. Top |