Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2009
  • Volume: 2
  • Issue: 2

Solubility Enhancement – Eminent Role in Poorly Soluble Drugs

  • Author:
  • Daisy Sharma, Mohit Soni, Sandeep Kumar, GD Gupta
  • Total Page Count: 5
  • Page Number: 220 to 224

Department of Pharmaceutics, ASBASJSM College of Pharmacy, Bela, Ropar, (Punjab) 140111, INDIA

*Corresponding Author E-mail: drgdg@rediffmail.com

Abstract

Among all newly discovered chemical entities about 40% drugs are lipophillic and fail to reach market due to their poor water solubility. The solubility behaviour of drugs remains one of the most challenging aspects in formulation development. Solid dispersions have tremendous potential for improving drug solubility. The present review is devoted to production of solid dispersions, various carriers used and the advantageous properties of solid dispersion.

Keywords

Solid dispersion, solubility, eutectic mixture, poorly soluble