Neuroleptic malignant syndrome: A review of diagnosis and treatment Putra Patria Yudha1, Setawat Yunias2,* 1General Practitioner, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. 2Consultant Psychiatrist, PhD, Department of Psychiatry, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. *Correspondence Author: Consultant Psychiatrist, PhD, Department of Psychiatry, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Email: yunias.setawat@gmail.com
Online published on 26 August, 2021. Abstract Background Neuroleptic Malignant Syndrome is a life-threatening neuropsychiatric emergency because of the use of Neuroleptic drugs characterized by specifically clinical syndrome, like changes in mental status, stiffness, fever, and dysautonomia. The current problem in managing of the Neuroleptic Malignant Syndrome is still not yet optimized causing the death rate is quite high with an incidence rate of the Neuroleptic Malignant Syndrome is ranging from 0.02 to 3 percent among patients taking anti psychotic agents occur throughout the world. Methods From published articles conducted by the experts that concerning in Neuroleptic malignant syndromes and its management have been considered and reviewed. Comments It is important for medical workers to understand steps in managing and treating Neuroleptic Malignant Syndrome from the initial management such as the immediate termination of Neuroleptic Malignant Syndrome drug agents, giving supportve management, early detection of clinical symptoms, Prevention of risk factors untl understanding the medical conditons associated with Neuroleptic Malignant Syndrome specifically. Top Keywords Neuroleptic Malignant Syndrome, Early Detection, Prevention, Risk Factor, Schizophrenia, Psychiatry Emergencies, Complication of anti-psychotic drugs. Top |