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Open Journal of Psychiatry & Allied Sciences
Year : 2021, Volume : 12, Issue : 2
First page : ( 105) Last page : ( 108)
Print ISSN : 2394-2053. Online ISSN : 2394-2061.
Article DOI : 10.5958/2394-2061.2021.00023.9

Verbal learning in schizophrenia in remission, first-degree relatives, and correlation to symptoms

Chattopadhyay Sunny1*, Singh Om Prakash2, Ghosh Sayanti3

1Department of Psychiatry, NRS Medical College, Kolkata, West Bengal, India

2Department of Health and Family Welfare, Government of West Bengal, India

3Department of Psychiatry, NRS Medical College, Kolkata, West Bengal, India

*Correspondence: Sunny Chattopadhyay, K-19, Kestopur Road, Block-2, Teachers’ Housing Society, Burdwan-713104, West Bengal, India, sunny11802001@gmail.com

Online Published on 11 April, 2022.

Abstract

Background

Cognitive impairments are fundamental in schizophrenia with verbal memory impairments commonly occurring not only in patients but also in unaffected genetically susceptible individuals. Deficits in verbal memory produce difficulty in problem-solving, emotional distress, and worsening of daily life skills resulting in a poor quality of life.

Objectives

This study aims to evaluate the verbal memory in unaffected first-degree relatives of patients of schizophrenia in comparison to healthy controls as well as patients of schizophrenia in remission and to find correlation to symptom domains.

Methods

It was a hospital-based, descriptive, cross-sectional case-control study. Three groups (n=40, each group) of patients, first-degree relatives, and controls were taken. Subjects were screened for mental retardation and remission was ascertained in the patient group by the Positive and Negative Syndrome Scale (PANSS). Rye's Auditory Verbal Learning (RAVL) test was used to assess verbal leaning.

Results

Verbal memory impairments were significant both in patients and unaffected first-degree relatives. Further, these impairments showed a strong correlation to negative symptoms.

Conclusion

Significant (p<0.05) verbal learning impairments were noted in patients and first-degree relatives which showed a correlation to negative symptoms.

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Keywords

Retention, Recall, Cognitive Deficit, Psychosis, Memory.

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