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Research Journal of Pharmacy and Technology
Year 2023, Volume-16, Issue-12 (December)
Print ISSN: 0974-3618
Online ISSN: 0974-360X

Table of Contents

Research Articles

Severe Traumatic Brain Injury Induced Coagulopathy in Pediatric: An Important Lesson with Literature Review
Muhammad Reza Arifianto, Wihasto Suryaningtyas, Muhammad Arifin Parenrengi

Design and Characterization of Oral Mucoadhesive Buccal Films of Empagliflozin
Ramu Samineni, Shaik Firoz, Nagaraju Bandaru, Swagat Lenka, P. Pravallika, S. Ooha, Sampath A Gouru, M. Sivakumar

Reverse Phase Liquid Chromatography for Cetrimide Determination in Pure and Pharmaceutical Preparations
Ziad T I Alkayar, Ahmed A. Ismail, Nagham Muthanna Jassim Al-Ani, Fedoseenko Anastasia Alekseevna, Ahmed Mahdi Saeed, Haider Mahmoud Nasser Al-Amir, Mahmood Shakoori Yaseen, Bashaar Mohammed Tawfiq, Zena M. Jassem, Shaimaa Ahmad Hassan, Maryam O. Abd Ala

Antioxidant activity test of Macerated extract and Sonicated extract of Areca nut (Areca catechu L.)
Nutrisia Aquariushinta Sayuti, Agus Kirwanto

Standardization of organic manures on growth of winter cherry (Withania somnifera)
Suresh, V, R. Kousalya, B. Gopu, J. Kabariel, A. Rajkumar

Determination of the Anti-bacterial potency of Allium sativum (Garlic) extract against Agrobacterium tumefaciens causing Crown Gall Disease
S. Hemaa, P. Sankarganesh, V. Parthasarathy, R. Anbarasan

Investigation of Oil in Water Emulsion properties depending on the change of Emulsifiers combinations
Zhanna Polova, Tetiana Nehoda, Tetiana Butkevych

Antiviral Investigation of Cassia alata L. bioactive compounds for SARS-CoV-2 Mpro: In Silico approach
Dora Dayu Rahma Turista, Viol Dhea Kharisma, Arif Nur Muhammad Ansori, Karina Ahmedovna Kardanova, Islam Ruslanovich Aslanov, Ibragim Muhadinovich Dotkulov, Azret Zamirovich Apshev, Amir Albertovich Dokshukin, Maksim Rebezov, Vikash Jakhmola, Md. Emdad Ullah, Rahadian Zainul

Development and Validation of a New HPLC Method for the Estimation of Sulfamoxole in Bulk and Tablet Formulations
Kamala Karuna Moparthy, Venkata Nadh Ratnakaram, Giri Prasad Gorumutchu

GC-MS Analysis of Phytocomponents of Methanolic Bark Extract of Sterculia foetida
Koushik Jana, Abhijit Ghosh, Biplab Debnath, Sonjit Das

Evaluation of Antioxidant and Dermato-protective activities of Origanum vulgare extracts
Nadjiba Belhacini, Karima Alem, Amel Boumendjel, Mahfoud Messarah

Accumulation of heavy metals in water and sediments Moroccan Atlantics estuary
Samar Aarabi, Oussama Chauiyakh, Oumaima Ninich, Elmostafa El Fahime, Kamal Kettani, Aziz Et-Tahir

Phytochemical Screening and Green Synthesis of Antibacterial Silver Nanoparticles of Sapindus mukorossi Fruit Extracts
Yogita Ale, Shilpa Rana, Nidhi Nainwal, Shivani Rawat, Mansi Butola, Rahadian Zainul, Vikash Jakhmola

Accuracy of Nasal House Dust Mite-Specific Immunoglobulin E in Diagnosis of Local Allergic Rhinitis
Elsa Rosalina, Dwi Reno Pawarti, Irwan Kristyono, Baharudin Abdullah

Standardization of Hibiscus rosa-sinensis Flower by HPTLC, HPLC and AAS
Arpan Chakraborty, Arka Bhattacharjee, Manas Chakraborty, Goutam Mukhopadhyay

Vulvovaginal atrophy screening in Perimenopause – A Forsaken practice in Gynaecology
Megha Tiwari, Neema Acharya, Samarth Shukla, Shazia Mohhamad

In-vivo and In- vitro Antidiabetic potential of Musa balbisiana colla and its different parts
Daisy Sharma, Manash Pratim Sarma, Chandana Choudhury Barua, Radali Duarah, Pameena Narzary

Spectrophotometric Multi-Component Quantitation of Rosiglitazone, Glibenclamide and Metformin HCl in Pharmaceutical Dosages Form by using Cramer’s Matrix
Uttam Singh Baghel, Abhay Sharma, Harshit Gautam, Mohammad Mukim, Deeksha Singh, Shuchi Dave, B. Srivastava, Bhawani Singh

Evaluation of Antitumor Activity of Sivanar Amirtham – A Herbomineral Formulation belonging to Indian Traditional System of Medicine using Dalton’s Ascites Lymphoma in Mice
Moushumi Baidya, Shvetank Bhatt, Himangshu Sekhar Maji, Kuntal Manna, J. Anbu

Effect of Tempuyung (Sonchus arvensis L.) Leaf Extract on Kidney Histology of Mice Exposed to Plasmodium berghei
Dwi Kusuma Wahyuni, Rizal Adistya Putra Pradana, Sri Puji Astuti Wahyuningsih, Hery Purnobasuki, Manikya Pramudya, Sehanat Prasongsuk, Sumrit Wacharasindhu, Tope Gafar Atere

Development and Characterization of Polyherbal Anti-acne face gel using Liquorice and Palash extract
Payal N. Vaja, Chetan H. Borkhataria, Hiral S. Popaniya

Anti-inflammatory activity of Methanolic extract and Quercetin from the leave of Carica papaya Linn (Caricaceae)
Vaibhav Kumar Sharma, Veena Devi Singh, Avijit Mazumder, Vijay Kumar Singh, Sanjay J. Daharwal

Solid Dispersions: An Effective Technology for Improving Dissolution Kinetics of Poorly Soluble Drugs
Ranim Alrouhayyah, Tatiana F. Sheshko, Svetlana N. Suslina, Omran Aisha

Hepatoprotective effect of Swertiamarin from Cytarabine Induced Hepatotoxicity in Pregnant rats
Rajini Kolure, Nachammai V, S N Manjula, Ramreddy Godela, D Sherisha Bhavani, Y Rajendra

Formulation and Evaluation of Nanosponge-based Drug Delivery System of Aceclofenac for Topical application
Manishkumar Gupta, Birendra Shrivastava, Aditya Ghuge, Neha Dand

Wastewater treatment by infiltration percolation process using fine sand and activated carbon
Safae EL Aammouri, Noura Benlemlih, Mohammed IBRIZ

Pharmacognostic and Phytochemical Characteristics of the Colchicum luteum Baker (Suranjan) growing wild in Kashmir Valley, India
Mohammmad Younis Dar, Md Sajid, Riehana Gani, Abdul Jalil Shah, Rampratap Meena, Seema Akbar, Tariq Ahmad Malik

Comparative efficacy of two Kokilaksha Formulations vis-a-vis Vinblastine, using Seed Germination Inhibition
Mrinalini Menon, Akshata G. Athreya

Characteristic and Formulation Turmeric Extract Nanoemulsion as Alternative Moisturizer in Atopic Dermatitis
Suryawati N, Indira IGAAE, Wardhana M, Sumardika IW, Indrayani AW, Arimurni DA, Chabib L

A Study on Evaluation of Drug Package Inserts in Kashmir, India
Zuryat Ashraf, Saima Bashir, Iram Kahkashan, Mehwish Majeed, Samina Farhat

Analytical Methods of Estimation of Oxetacaine and its quality determinations in different Pharmaceutical Formulations by Reverse Phase High Performance Liquid Chromatography (RP-HPLC)
Kirubakaran N., Umashankar M. S., Bhuvaneshwari S.

Correlation between Transforming Growth Factor-Beta Levels and Skin Disorder Levels based on Modified Rodnan’s Skin Scores in Systemic Sclerosis Patients
Zuhria Novianty, Anna Tjandrawati, Tiene Rostini, Delita Prihatni, Sumartini Dewi

Profession for the Magnitude of Temperature and Exposure time on Opuntia elatior cladode extraction on percent yield using design expert software
Hindustan Abdul Ahad, Mazin Aboobaida Abdalla Abdelaziz, Hossamaldeen Bakrey, Abdulkadir Abdu, Yassin Babkir Elshiekh Mohamed, Amal A. Noureldeen

Qualitative Chemical Plant Characterization and Evaluation of the Antioxidant and Antimicrobial potential of Rhododendron, a high Attitudinal Medicinal Plant in Uttarakhand, India
Kumari Rashmi, Amit Gupta, Kaniska, Rakesh Pant, Priyank Vyas, AB Bajpai

Cardioprotective effect of Extract Ethanol Ocimum basilicum on Rat Induced Cisplatin
Desi Prawita Sari, Jekson Martiar Siahaan, Hendrika Andriana, Reza Yuridian Purwoko, Binarwan Halim

Comparative Evaluation of Formulations Designed using Chemically Modified Pectin and Eudragit for Sustained Release of Nateglinide
Anilkumar J. Shinde, Sachin S. Khandekar, Manish S. Bhatia, Firoj A. Tamboli, Ravindra J. Jarag, Harinath N. More

Project management of the lifecycle of students’ research projects in higher pharmaceutical education
T.M. Litvinova, I.I. Galuzina, L.I. Babaskina, D.V. Babaskin, I.U. Glazkova, O.V. Savinova

Screening of Phytochemicals for Antisickling effects
Sudama Rathore, Viplav Prashant, Dolly Prashant, Abhigyan Nath, A. Shivram

Histochemical analysis of Xanthium strumarium raw materials, growing on the territory of Kazakhstan
Itzhanova H. I., Remetova N. S., Ishmuratova M. Yu., Nogayeva A. N., Abdrakhmanova G.M., Medeshova A.T., Samorodov A.V.

Prediction of In-silico ADMET Properties and Molecular docking study of Substituted Thiadiazole for screening of Antiviral activity against protein target Covid-19 main protease
Deshmukh Nitin, Soni Love Kumar

Therapeutic effects of Okra (Abelmoschus esculentus L.) and Iron Supplementation on Hemoglobin Level among Pregnant women
Agnes Purba, Santhana Letchmi Panduragan, Satheesh Babu Natarajan, Rinawati Sembiring, Henny Syapitri, Ruma Poddar

Molecular Docking of Fisetin as a Multi-target drug in the treatment of Alzheimer’s disease
Malathi R, Vailina Dsouza, Puja, Rithika R, Sneha P

Dissolution Method for Estimation of Deflazacort in Tablet Dosage Form by UV Visible Spectroscopy
Ashok B. Patel, Bansil Bhalodiya, Jyotishna B. Choudhary, Amitkumar J Vyas, Ajay I. Patel, Nilesh K. Patel, Devang B Sheth, Sandip Dholakiya

Pharmacopoeial Compliance of Marketed Formulations containing seeds of Syzygium cumini (L.) Skeels
Nartunai Govindarajan, Lokesh Ravichandran, Prem Kumar Chelladurai, Akansha Pandey, Vendal Murugesan, Ganji Kusuma

Pharmacognostic Study of Butea monosperma a versatile medicinal plant
Meenakshi Sharma, Raj Kumari, Prasoon Kumar Saxena

Study the influence of Mutagenic Treatment on Cell Suspension Culture of Elephantopus scaber L. for the Quantitative enhancement of Bioactive constituents and their Antioxidant potentials
Sopan N. Kharat, Vijay D. Mendhulkar

Review Article

Potential of Indian herbs and herbs derived compounds in the treatment of Acne – A Commonly occurring skin disease: A Review
Poulomi Biswas, Kaushik Biswas

Research Articles

Hepatoprotective effect of Pippali Ghrita, an Ayurvedic Formulation against Anti-Tubercular Drug Induced Hepatotoxicity in Wistar Rats
Vedvati K. Bhapkar, Nilesh L. Suryawanshi, Archana P. Gharote, Vinay A. Pawar, Mrudul Y. Chitrakar

Correlation of Vitamin D Levels with Insulin Resistance in women with PCOS
Salmon Charles P T Siahaan, Areta Idarto, Sarah Hagia Lestari, Fatimah Usman, Ferdinand Aprianto Tannus

Whey preparation as an adjuvant to minimise the Intestinal inflammatory status in mucositis rat model
Sudarshan Reddy, Gayathri M Rao, Aradhana Marathe, Saritha Kamath

Tuna Ethanol Extract reduces CRP and Edema in Animal Models of Adjuvant Arthritis
Fitri Handajani, Judya Sukmana

Formulation, optimization, characterization and evaluation of Simvastatin loaded solid lipid nanoparticles using quality by design approach
Katkade P.N., Zalte A. G., Gondkar S. B., Darekar A. B., Amrutkar S. V.

Phytochemical characterisation, antioxidant and anti-microbial efficacy of allspice Pimenta dioica
K. Nagalakshmi, R Monica Angeline, G. Sriram Prasath

Functional Outcome of Inter-Trochanteric and Sub-Trochanteric Fracture Femur Treated with Proximal Femur Nail Antirotation-II
Shivaji Avate, Kiran L. Gaonkar, Madhuranjan Vatsa, Kumari Lipi, Sudhir Patil

Non-Tuberculous Mycobacteria Infections based on 16S rRNA detections in patients with Suspected Chronic Tuberculosis at a Tertiary Referral Hospital in Indonesia
Deby Kusumaningrum, Ni Made Mertaniasih, Soedarsono

Utility of Automated Reticulocyte Research Parameters derived from Beckman Coulter DXH800 in Nutritional Deficiency Anaemias
Ruchee Khanna, Muneerah Saeed, Chethan Manohar, Varun K. Singh

A Clinical Case Study on Janu Sandhivata (Knee Arthritis) to evaluate the effect of Combined Panchakarma procedure and Internal Traditional Ayurvedic Formulations
Dipsundar Sahu, Saroj K. Debnath, Debajyoti Das, Laxmidhar Barik, Ranjita Ekka, Suparna Saha, Tushar K. Madal, G. Babu

Effect of Teneligliptin in comparison with Voglibose as an add on therapy in reducing microvascular complications in type II Diabetes Mellitus patients – A Prospective randomized control trial
V. Sivasankari, E. Manivannan

The Influence of the coating on the release of Ibuprofen from the Tablet: Comparative Dissolution Study of the different types of coating
Ismail Bennani, Ali Cherif Chefchaouni, Hajar Benhaddou, Madiha Chentoufi Alami, Badreddine Moukafih, Soufiane El Marrakchi, Aicha Fahry, Yassir El Alaoui, Younes Rahali, Abdeslam El Kartouti, Youssef Hafidi, Abdelkader Laatiris, Nawal Cherkaoui

Prediction of Structure Activity Relationship (SAR) of Lactobacillus plantarum DA2 content for Cholesterol Reduction Treatment
Dessy Abdullah, Sandeep Poddar, Nadia Purnama Dewi, Ade Teti Vani

Preparation, Characterisation and Antifungal activity of Silver Nanoparticles prepared with Fresh Extract of Aconitum heterophyllum leaves
Mohammad Akhtar Rasool, Girendra Kumar Gautam, Durga Prasad Panda, Arin Bhattacharya, Ritesh Jain

Clinical Management of Head Injuries with Conventional Therapy (Magnesium Sulfate, Hypertonic and Mannitol) with Phytomedicine (Propolis and Black Cumin) through the Parameters of the Glasgow Coma Scale
Tommy A. Nazwar, Farhad Balafif, Donny W. Wardhana, Mustofa, Christin Panjaitan

Assessment of Anti-Microbial Efficacy against Oral Pathogens, Anti-Inflammatory, and Anti-oxidant Activity of Ethanolic and Aqueous Extract of Erythrina variegata (Indian Coral Tree) Leaves – An In-vitro Study
Subhashree Mohapatra, Rahul Mohandas, Sri Sakthi Doraikannan

Computational Fluid Dynamics as a Simulation tool in the Formulation development of Parenteral and Biphasic Liquid Dosage Forms
Keerthana Bhandarkar, Vamshi Krishna Tippavajhala

Histochemical Study of above-ground parts of Prunella vulgaris L., growing on the Territory of the Republic of Kazakhstan
Zholdasbayev M. E., Ishmuratova M. Yu., Atazhanova G. A., Musozoda S. M., Ewa Poleszak

Neuroprotective Potential of Total Extract of Ulva Lactuca: An In vitro study
Naveen Kumari K, Srikanth Jeyabalan, Jayaraman Rajangam, N. Gopinathan, S.R. Ramakrishnan, V. Jayashankar Reddy

Antibacterial Activity of the Combination of Calcium Hydroxide and Ellagic Acid towards Enterococcus faecalis and Lactobacillus acidophilus
Intan Nirwana, Rr. Asti Meizarini, Priyawan Rachmadi, Titien Hary Agustantina, Koh Wan Huei, Eshleen Nisha Kumar, Naufal Zhaffrano Razan

Influence of Agro wastes on Enhanced Carotenoid Production – An Untapped Resource from Tropical Wetland Actinobacterial Cell Factory for Multifunctional Prospectives
P. Sai Preethi, N. M. Hariharan, K. Jyothsna Devi, Rameshpathy Manian

Quality Control Analysis of Neomycin, Gramicidin and Triamcinolone in Ointment Formulation using HPLC Methodology: Methodology Development, Validation and Application
M.S. Swarna Pushpa, T. Raja Rajeswari

Prescribing Pattern of Antimicrobials for Respiratory Tract Infections among Paediatric population in a Multi- Speciality Teaching Hospital
Mushrifa Hishmath, Zaheema A P, Sajan Francis P, Vinitha K, Grinton Josvi Veigas, Ravikumar

Phytoconstituents profiling of Selaginella willdenowii (Desv.) Baker and Pharmacological Potential
Susilo Susilo, Ratih Kusuma Wardhani

Quantification of Vortioxetine in Pharmaceutical preparations by validated area under curve UV Spectrophotometric Analytical method
Santosh Karajgi, Sushma Angadi, Shripad Potadar

Quality Evaluation and Effectiveness of Palmarosa (Cymbopogon martinii var. motia) Essential oils as repellents against Aedes aegypti
Nastiti Utami, Novena Yety Lindawati, Tiara Karunia Kristy

Spectrometric Bioanalytical Method Development and Validation of Tolvaptan in Spiked Human plasma Followed by Forced degradation Studies
K. Bhavyasri, B. Aishwarya, D. Suchitra, M. Sumakanth

Development a New Diagnostic Based on Autoimmune Markers for Hashimoto Thyroiditis
Dyah Kinasih Wuragil, Djoko Wahono Soeatmadji, Achmad Rudijanto, Agustina Tri Endharti, Aulanni’am Aulanni’am

Effect of Irrigation Solution of Sodium Hypochlorite, Ethylenediamine Tetraacetic Acid, Chitosan Oligosaccharide and Agitation Techniques on Calcium Hydroxide Removal in Root Canal: In Vitro Study
Melia Heptania, Trimurni Abidin, Widi Prasetia, Basri A. Gani

Biosynthesis of Silver Nanoparticles from Spirulina: Enhancement of Antibacterial, Antidiabetic and Antioxidant Activities
Nivas Balaji Venkatesh, Muthu Laxmi Veerappan, Kulandhaivel Murugesan

Evaluation of the Hepatoprotective potential and Antioxidant activity of 4–Hydroxybenzyl alcohol on Carbon tetrachloride Induced liver damage in Experimental animals
Pradeep Kumar Samal, Bharti Vaishnaw, Bharti Ahirwar, Kedar Prasad Meena, Aarti Tiwari, Kamdev Sen, Dipendra Nirmalkar, Pameshwar Sahu, Geetanjali Darsena

Review Article

Phytosomes: A Novel approach for improving the efficacy of Herbal Extracts
M. Saritha, A. Ramya, A. Sonia, S. Monika, K. Sowmya

Research Articles

Kadukkai maathirai (Siddha herbal formulation) reverses liver pathology associated with metabolic dysfunction in high fat diet-induced fatty liver disease – A preclinical study
Manjunath Shetty, Smita Shenoy, Nitesh Kumar, Arul Amuthan, Ganesh Shenoy, Vasudha Devi, Akshatha, Mohandas Rao

HPLC Method Development and Validation for Residue Analysis of Steroid
Urvi Das Sharma, Ganesh CH, Ruchi Verma, Lalit Kumar

Quantitative Estimation of Variability in Content of Asiaticoside in Centella asiatica Linn Collected from Different Geographical Regions of India by HPLC
Ajay Kumar Meena, P. Rekha, K. N. Swathi, C. Sadhna, M. Gokul, R. Ilavarasan, N. Srikant

Review Articles

A Clinical Review on Ulcerative Colitis (Colon Cancer)
A. Muthukumar, Bhavani Keserla, Syed Mohasin Abbas, Reena Thapa, Rumana Khatija

Role and Responsibility of Allicin for the Prevention of Cardiovascular Diseases: A Systematic Review
Ayan Chatterjee, Parna Chatterjee, Ashi Ramavat

Diabetic Nephropathy: Pathogenesis and Drug Delivery System
Nurul Jummah, Satrialdi, Aluicia Anita Artarini, Anindyajati, Diky Mudhakir

Insomnia Management Clinical Trials by various Conventional Therapies – A Review
Maanickha Chelvi KS, Karthik Nagarajan S, Kanagarajan A

A Review on Thiazole derivatives and their impact as hypoglycemic agents in drug developments
Gupta Dheeraj Rajesh, Pankaj Kumar, Abhishek Kumar, Sachin A Kumbar, Vidya Murugeshwari, Seshagiri R Dixit

Aquasomes: A Nanoparticulate approach for the Delivery of Drug
Prathamesh L. Shirole, Dhanashree P. Sanap, Kisan R. Jadhav

Applications of Polymeric Nanoparticle in Nose to Brain Drug Delivery
Sunena, Sumit Kumar, Sulekha, Deepali Tomar, Dinesh Kumar, Vimal Kishore

A Review on Oleogels and its Role in Pharmaceutical Field
Amaresh Prusty, Chaithanya Sudha

Fast Dissolving Oral Films: Formulation, Evaluation and Future aspects
Muniraj Bhattacharya, Oindreela Sarkar, Pintu K. De

Chitosan- A Promising agent for site specific drug delivery in periodontics
Nishmitha D. Shetty, Deepa G. Kamath, Neetha J. Shetty

Research Article

Analytical method development and validation for the estimation of Rilpivirine and its N-Oxide impurity using UPLC
Varada Soujanya, Revu Baby Nalanda

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