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Research Journal of Pharmacology and Pharmacodynamics
Year : 2022, Volume : 14, Issue : 4
First page : ( 237) Last page : ( 245)
Print ISSN : 0975-4407. Online ISSN : 2321-5836.
Article DOI : 10.52711/2321-5836.2022.00041

Incidence of moxifloxacin serious adverse drug reactions in pneumococcal infections virus infected patients detected by a pharmacovigilance program by laboratory signals in a Tertiary Hospital in Chhattisgarh (India)

Dewangan Vandna*, Sahu Ram Kumar, Satapathy Trilochan

Department of Pharmacology, Columbia Institute of Pharmacy, Near Vidhansabha, Village Tekari, Raipur, (C. G.), India - 493111

*Corresponding Author E-mail: vandnadewangan543@gmail.com

Online published on 9 March, 2023.


The direct reporting of adverse drug reactions by patients is becoming an increasingly important topic for discussion in the hospital of Pharmacovigilance. Voluntary adverse drug reaction (ADR) reporting is fundamental to medical drug safety surveillance; however, substantial under-reporting exists and is the main limitation of the system. At this time, hospital accepts consumer reports. The World Health Organization estimates that in 2005 and as well as 2019–2021 pneumococcal infections were responsible for the death of 1.6 million human worldwide. Pneumonia, the lungs become filled with fluid and inflamed, leading to breathing difficulties. For some people, breathing problems can become severe enough to require treatment at the hospital with oxygen or even a ventilator. The pneumonia that COVID-19 causes tends to take hold in both lungs. Moxifloxacin, a fluoroquinolone antibiotic, is used for the treatment of respiratory tract, pelvic inflammatory disease, skin, and intra-abdominal infections. Its safety profile is considered favorable in most reviews but has been challenged with respect to rare but potentially fatal toxicities. The most common adverse drug reaction (ADR) constipation is nausea, vomiting, fatigue, alopecia, drowsiness, myelosuppression, skin reactions, anorexia, mucositis, diarrhoea and Medicines that have been particularly implicated in adverse drug reaction-related hospital admissions include anti-platelets, anticoagulants, cytotoxics, immunosuppressant's, diuretics, anti-diabetics and antibiotics.



Moxifloxacin, Pneumonia, Adverse drug reactions, Antibiotic, Fungi, Intra-abdominal infections, Acute bacterial sinusitis, Fatigue, Serious cutaneous reactions, Inflammation, Adverse event, Difficulty breathing.


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