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Year : 2010, Volume : 11, Issue : 2
First page : ( 360) Last page : ( 365)
Print ISSN : 0972-1738. Online ISSN : 2249-8796.

Liver Diseases in Dogs- A Prospective Study

Dixit Pooja1, Varshney J. P.2Consultant (Medicine), Dixit A. K.3, Shukla P. C.4

Division of Medicine  Indian Veterinary Research Institute Izatnagar  Bareilly-243 122 (Uttar Pradesh)

1Department of Veterinary Medicine, College of Veterinary Science & A. H., MPPCVV, Rewa

2Nandini Veterinary Hospital, Ghod-Dod Road, Surat-395007

3Department of Veterinary Parasitology, College of Veterinary Science and A.H., MPPCVV, Rewa

4Department of Veterinary Medicine, College of Veterinary Science and A.H., Jabalpur

Online published on 20 October, 2011.


One hundred forty dogs with hepatopathies, diagnosed employing a battery of tests, were investigated for clinico-epidemiological variants. Of these 82 dogs were having primary and 58 were having secondary hepatopathies. Primary hepatopathies were differentiated as hepatitis/hepatosis, cirrhosis/fibrosis or intrahepatic portosystemic shunt and extra-hepatic diseases causing hepatic reaction and responses were blood protozoan and rickettsial diseases, haemorrhagic gastroenteritis simulating to parvo, epilepsy, pyometra and hydronephrosis. Clinical signs were vague and varying from decreased appetite, anorexia, nausea/vomiting, ascites, weakness, weight loss, pale mucosa, epigastric pain, pyrexia, bilateral hind limb odema, constipation, diarrhoea, melena, icterus, encephalopathy, polyuria/polydipsia to depression in different combinations. Melena with ascites and bilateral hindlimb odema were most commonly associated with cirrhosis or intrahepatic portosystemic shunt. It was also interesting to note that the growth was stunted in cases of intrahepatic portosystemic shunt. Nervous signs viz. ataxia, hypersalivation, head pressing, seizure, behavioural changes were associated with cirrhosis or intrahepatic portosystemic shunt. Target cell, spherocytes, poikilocytes and acanthocytes were seen in advanced cases of cirrhosis or intrahepatic portosystemic shunt. The mean median age of the dogs with hepatic diseases, was higher than that of dogs showing hepatic reaction and responses to extrahepatic diseases. The mean age of dogs with intrahepatic PSS was lower. Hepatitis and cirrhosis were more prevalent in females and intrahepatic PSS in males. Amongst breeds, Pomeranians were over represented for primary or secondary hepatopathies.


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