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Listeria ivanovii upregulate expression of OvCD4 and OvCD8 T-cell antigens in naturally infected ewes Khatri M., Sharma R., Chand P. Department of Veterinary Microbiology, College of Veterinary Sciences, CCS Haryana Agricultural University, Hisar, (Haryana) - 125004. Abstract Four naturally infected ewes with Listeria ivanovii were investigated to examine the proportions of T lymphocyte subpopulation in peripheral blood. The levels of lymphocyte subpopulation were analysed in cytosmears of peripheral blood mononuclear cells by enzyme immuno-assay employing OvCD4, OvCD8 and OvCD5 specific monoclonals. Infected ewes had significantly increased proportions of both OvCD4+ and OvCD8+ T lymphocytes than uninfected ewes of the same age (P<0.005). However, the proportion of OvCD5+ T lymphocytes were not significantly different from that of uninfected ewes. The ratio of OvCD4+ and OvCD8+ T lymphocytes remained at low ebb during the infection. Top Key words Listeria ivanovii, OvCD4, OvCD8, T-cells, Ewes. Top | | |
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