Animal Nutrition and Feed Technology

An experiment was conducted to study the effects of Pichia pastoris residue (PPR) supplementation diet on growth performance, nutrient digestibility, plasma amino acids, biochemical profile, and immunoglobulin of weaned piglets. A total of 48 piglets with an initial body weight of 8.99±0.23 kg were allocated randomly to three diets containing 0% (T0), 8.7% (T1), and 17% (T2) of PPR levels, for 28 days.The dose selection was based on protein quantity of SBM and PPR in diet.The average feed intake and daily weight gain decreased in T1 and T2 significantly (P<0.05) compared to T0 (control). However, the feed gain ratio was not affected. Apparent total tract digestibility of crude protein and fiber reduced (P<0.05) in treatment groups as compared to T0. The plasma concentration of lysine and threonine were not affected but methionine, isoleucine, phenylalanine, and valine, decreased significantly in T1 and T2, whereas cysteine increased (P>0.05). Blood total protein and albumin decreased in T2 in comparison to T0, whereas glucose, triglycerides and urea nitrogen remained unchanged. The diet with a low level of PPR improved the immunoglobulin IgG and did not affect IgM in piglets. In conclusion, only two biochemical parameters, glucose and triglyceride improved in both treatments, plasma immunity only in T2, although there was a significant depression in the growth performance.