Synthesis and Juvenile Hormone Mimetic Activity of 3,7-Dimethyl-2,6-octadien-1-aldoxime-N-O-alkyl ethers

3,7-Dimethyl-2,6-octadien-1-aldoxime-N-O-alkyl ethers have been synthesized, separated into their four isomers viz, 3,7-dimethyl-2(E),6-octadien-1-(E)-aldoxime N-O-alkyl ether, 3,7-dimethyl-2(Z),6-octadien-1-(Z)-aldoxime N-O-alkyl ether, 3,7-dimethyl-2(E),6-octadien-1-(Z)-aldoxime N-O- alkyl ether and 3,7-dimethyl-2(Z),6-octadien-1-(E)-aldoxime N-O- alkyl ether and characterized on the basis of ¹H-NMR and mass fragmentation pattern. They have been evaluated for their juvenile hormone mimetic activity against red cotton bug, Dysdercus koenigii. Maximum JH mimetic activity has been shown by 3,7-dimethyl-2,6-octadien-1-aldoxime-N-O-butyl ether (3.1458 μg per insect). Structure activity relationship studies revealed that maximum activity was associated with compounds having four carbons atoms in the oxime ether moiety.