1Department of Botany, Sri Sarada College for Women (Autonomous), Salem-63 6 016, Tamil Nadu, India
2Department of Botany, PSGR Krishnammal College for Women, Coimbatore-641 004, Tamil Nadu, India
*Corresponding author: Email: umabot@yahoo.com
Online published on 25 January, 2016.
The methanol extract of leaf, stem and root ofAmpelocissus araneosa (Vitaceae) at an oral dose of 200 mg kg"1 and 400 mg kg"1 was evaluated for hepatoprotective activity in Wistar albino rats with paracetamol induced liver damage. Methanol leaf extract (400 mg kg"1) showed significant protective effect by lowering the serum levels of various biochemical parameters such as serum glutamic oxaloacetate transaminase (SGOT), serum glutamic pyruvate transaminase (SGPT), alkaline phosphatase (ALP) and total bilirubin. The extract at this dose also increased the level of total protein. The activity of extract was also comparable to that of silymarin, a known hepatoprotective drug
Ampelocissus araneosa, hepatoprotective, silymarin, paracetamol
