1Division of Veterinary Biochemistry
2Division of Veterinary Microbiology and Immunology, Faculty of Veterinary Sciences and Animal Husbandry (FVSc & AH), S.K. University of Agricultural Sciences and Technology of Kashmir, Shuhama, Srinagar, 190 006, J&K, (India)
*e-mail: manzoorvbc@yahoo.co.in
Online published on 27 November, 2015.
Bovine mastitis, an important disease of dairy cattle, causes a significant change in normal milk composition as well as changes the overall blood biochemistry. We grouped the animals of Jersey and Holstein Frisian (HF) crossbred into normal, subclinical and clinical mastitis groups (n = 10 each) based on clinical history and diagnostic tests. The serum albumin showed a non-significant variation between the groups of both breeds following mastitis at subclinical and clinical stages. Mammary assosiated serum amyloid A3 (M-SAA3) protein in serum of Jersey crossbred cows showed non-significant difference between the groups, while in milk significant rise in M-SAA3 levels between mastitic groups was observed. In HF crossbred, there was significant increase in M-SAA3 levels in both milk and serum. The study revealed that M-SAA3 is a positive acute phase protein (APP) in both milk and serum and could be used as an adjunct biomarker to diagnose subclinical mastitis.
Acute phase protein, biomarker, albumin, bovine, mastitis, M-SAA3
