Bukhara State Medical Institute, Institute of Bioorganic Chemistry of the Academy of Sciences, Republic of Uzbekistan
*Email id: ranoboboyeva3553@gmail.com
Online published on 11 January, 2021.
In experimental animals on the model of acute tetra chloromethane hepatitis, a high choleretic activity of Rutan was established, which is not inferior in its effectiveness to Legalon. It is considered possible to further develop the drug as an effective choleretic agent in the prevention and treatment of pathologies of the hepatopancreatobiliary system. The animals were fed with natural and briquetted feed, in accordance with the approved standards. Experimental groups of animals were formed of 6 animals each, taking into account body weight. Moreover, in the latter, the duration of the hypnotic effect of sodium etaminal does not statistically significantly differ from the values of healthy rats.
Acute Toxic Hepatitis, Bile Formation, Polyphenols, Rutan