ACADEMICIA: An International Multidisciplinary Research Journal

  • Year: 2020
  • Volume: 10
  • Issue: 11

Efficacy of rosuvastatin and ezetimib combination for diabetic dyslipidemia in patients with type 2 diabetes

Tashkent Medical Academy, Uzbekistan

null

Abstract

One of the necessary drugs for the treatment of diabetic dyslipidemia affecting lipid metabolism is hydroxycis-methylglutaryl-coenzyme A-reductase inhibitors (statins) [2] and ezetimibe, which blocks the absorption of cholesterol in the epithelium of the small intestine, thereby preventing erythematic enterohepatic circulation of cholesterol [2,4]. Their effectiveness in correcting atherogenic dyslipidemia (DLP) and preventing macroangiopathieshas been studied in patients with diabetes mellitus (DM). The aim of this study was to study the lipid-lowering efficacy of the combination therapy of rosuvastatin with ezithymibe in patients with type 2 diabetes mellitus

Keywords

Diabetes Mellitus (DM), Lipid-Lowering Therapy, Rosuvastatin, Ezetimibe, Total Cholesterol (TC), Low Dencity Lipoproteins (LDL), High Dencity Lipoproteins (HDL)