Determination of molecular and genetic features and prevention of gastric and duodenal ulcer

To evaluate the molecular and genetic parameters of patients with gastric and duodenal ulcer. 100 patients with gastric and duodenal ulcer were examined. Of these, groups with complications (n = 49) and without it (n = 51) were selected, which were examined for polymorphic variants of the IL10 (G1C82A) and PGC-1A(G/A) genes by PCR. The IL10 (G1C82A), PGC-1A(G/A) are markers of the development of duodenal and gastric ulcer. Identification of candidate genes for peptic ulcer disease provides prevention of this pathology and plays an important role in the development of new approaches to the diagnosis and treatment of peptic ulcer disease.