ACADEMICIA: An International Multidisciplinary Research Journal

  • Year: 2020
  • Volume: 10
  • Issue: 5

Metabolic disorders in women depending on the duration of menopause

  • Author:
  • Tadjieva Malika Asralovna1, Zakirkhodjaeva Dildora Asralovna2, Navruzova Rano Sadikovna3, Mirkhoshimov Mirsobit Botirugli4
  • Total Page Count: 5
  • Page Number: 1548 to 1552

1Assistant, Department of Obstetrics and Gynecology, Pediatric Gynecology, Tashkent Pediatric Medical Institute, Tashkent City, Uzbekistan

2PhD, Department of Obstetrics and Gynecology, Pediatric Gynecology, Tashkent Pediatric Medical Institute, Tashkent City, Uzbekistan

3PhD, Department of Obstetrics and Gynecology, Pediatric Gynecology, Tashkent Pediatric Medical Institute, Tashkent city, Uzbekistan

4Student, Tashkent Pediatric Medical Institute, Tashkent City, Uzbekistan

Abstract

The menopausal period is almost one third in the life of women, thanks to this fact, not only the health of the woman, but also her ability to work, the ability to perform various social functions that depend on the nature and course of this period. One of the complications of the postmenopausal period are metabolic disorders. In order to study the degree of metabolic disorders depending on the duration of menopause, 75 women were examined. A study of the genealogical history made it possible to find the main clinical signs pathognomonic for the metabolic syndrome (type 2 diabetes mellitus in 32% of cases, arterial hypertension in 52%, early coronary heart disease in 36%, found in close relatives). The longer the menopause, the more pronounced signs of obesity, impaired fat and carbohydrate metabolism (increased cholesterol, triglycerides, low density lipoproteins, decreased high density lipoproteins, the development of insulin resistance). An elevated level of C-reactive protein (4.3 ± 0.6 mg/l) was found in women with a menopause of more than 5–7 years, which is a factor contributing to the development of vascular diseases. In 32% of patients with a menopause longer than 7 years, pronounced metabolic disorders such as type 2 diabetes mellitus were diagnosed, and in 48% of cases hypertension was diagnosed, therefore, timely diagnosis and metabolic correction will help reduce the risk of cardiovascular disease -vascular diseases and diabetes among women during menopause, as well as improving their quality of life.

Keywords

Postmenopause, Metabolic Disorders, Lipid Metabolism, Insulin Resistance