*Doctor of Medical Sciences, Head of the Department of Internal Diseases, No2, Samarkand State Medical Institute, Samarkand, Uzbekistan
**Assistant, Department of Pediatrics, Pediatrics, Pediatric Disease Propaedeutics and Higher Nursing, Urgench Branch of Toshkent Medical Academy, Urgench, Uzbekistan
***Doctoral Candidate in Cardiology Specialty, Department of Internal Diseases No2, Samarkand State Medical Institute, Samarkand, Uzbekistan
****Master, Department of Internal Diseases No.3, Toshkent Medical Academy, Toshkent, Uzbekistan
Online published on 10 August, 2020.
The latest data from the World Health Organization show that cardiovascular diseases have increased dramatically among female patients and in recent years have increased by 0.1–1% at the age of 45–54 years and by 10–15% at the age of 65–74 years. It is believed that depressive manifestations are detected more often in women than in men. The study included 307 patients diagnosed with unstable angina. The average age of patients was 69.4±8.9 years. The women were conditionally divided into 2 groups: The 1st group was made up of women younger than 60 years old (187), the 2nd group was made up of women older than 60 years old (120). Thus, women with anxiety disorders are susceptible to frequent angion attacks, which are not always covered by nitrates and the duration of treatment of these patients requires longer correction.
Patients with anxiety disorder have frequent cases of cytokine balance disorder and cases of IL10 819 C/T polymorphism.
Cytokine Imbalance, Women, Destabilization, Angina Pectoris, IL-10 C/T Gene
