*Doctor of Philosophy in Biological Sciences (PhD), Department of General Biology and Physiology, Karakalpak State University named after Berdak, Uzbekistan Email id: k.gulchi@karsu.uz
Online published on 27 August, 2020.
The long-term effects of toxic substances, 48 days, significantly reduced the hydrolytic capacity of carbohydrates in the small intestine of growing rats relative to carbohydrates. The decrease in hydrolytic capacity relative to polysaccharides observed in the initial hydrolysis phase of carbohydrates was expressed in the small intestinal secretion of α-amylase in the pancreas, a decrease in enzyme activity in the small intestinal chymus. Chronic exposure to toxicants leads to an increase in pancreatic tissue and enzyme activity in the blood due to a decrease in α-amylase activity in the small intestine. Decreased pancreatic secretion and increased secretion are indicative of pancreatic insufficiency.
Growing Rat, Lead Acetate, Phenylhydrazine Hydrochloride, Pancreas, Small Intestine Chymus, Blood, α-Amylase
