Assessment of the balance of intra-cardiac hemodynamics and glomerular filtration in anemia with different hemodynamic types of chronic heart failure

Renal fibrosis markers were evaluated in dynamics to study specific changes in the kidneys of patients with different hemodynamic types and functional classes of chronic heart failure with anemia and to evaluate the effectiveness of complex treatment. Renal fibrosis marker TGF-β₁levels in the blood were 2591.0 ± 108.4 and 755.0 ± 18.87pg/ml, respectively, in chronic heart failure with anemia and without anemia (p<0.01). This was indicative of a fibrosis process occurring in the kidney. After complex treatments with the addition of iron, the TGF-β₁ index decreased by 2.25 times (p<0.01), the clinical condition, quality of life and resistance to physical exertion changed significantly positively.