Characteristics of the study group and dynamics of pathogenetic markers on the background of different anti-coagulation modes

The efficacy of three modes of anticoagulant therapy (direct oral anticoagulant, hepatic heparinized, non-fractionated heparinized) was studied. It was found that with a comparable anti-inflammatory effect of standard therapy with the inclusion of an anticoagulant, low molecular weight heparin significantly more pronouncedly reduces the concentration of the thrombus formation marker D dimer in the peripheral blood; All studied anticoagulation regimens significantly reduce the risk of thrombosis of the PA branches, with a more pronounced effect of low-molecular-weight heparin established; markers of resistance to anticoagulant therapy were found in patients with COVID-19 against the background of type 2 diabetes: hyperglycemia, greater volume of pulmonary parenchymal lesions, and pancreatic dilatation.