ACADEMICIA: An International Multidisciplinary Research Journal
  • Year: 2022
  • Volume: 12
  • Issue: 5

Synthesis of biologically active compounds based on o-ferrocenylbenzoic acid

  • Author:
  • Askarov Ibragim Rakhmonovich1, Madrakhimov Gairatjan Nematjonavich2, Khadjhimatov Makhsadbek Muydinovich3
  • Total Page Count: 8
  • Page Number: 225 to 232

1Professor of the Department of Chemistry, Andijan State University, Doctor of Chemical Sciences, Uzbekistan

2Doctoral Student, Andijan State University, Uzbekistan, Email id: madrahimov80@bk.ru

3Associate Professor of the Department of Chemistry, Doctor of Chemical Sciences, Andijan State University, Uzbekistan, Email id: m_xojimatov@mail.ru

Online Published on 14 July, 2022.

Abstract

The article provides information on the importance of biologically active compounds derived from ferrocene, one of the important representatives of metallocenes, in the chemical industry, medicine, pharmacology, on the synthesis of an o-ferrocenylbenzoic acid derivative with amygdalin ([(6-O-fi-D-glucopyranosyl -4-O-(o-ferrocenylbenzoyl)-fi-D-glucopyranosyl) oxy]phenyl) acetonitrile), reaction with monomethylol-urea and reaction product (1-(2-carboxyphenyl)-1’-N-methyloxy-ferrocenylamide), as well as the results of IR and mass spectral analysis and study of the biological activity of water-soluble salts of the obtained compounds.

Keywords

Ferrocene, N-Complex, Physiological Activity, O-Ferrocenylbenzoic Acid, 1-(2-Carboxyphenyl)-1’-N-Methyloxyferrocenamide, AKHM, IR Spectroscopy, Mass Spectrometry