Determination of the elemental and amino acid composition of the diuretic drug “Ekustim”

The purpose of these studies is to determine the elemental and amino acid composition of the diuretic drug “Ekustim” dry extract obtained from a mixture of 8 medicinal plants: false amber grass, woolly willow grass, horsetail grass, creeping anchor grass, yarrow flowers, cucumber seeds, corn stigmas and licorice roots. Quantitative determination of macro - and microelements was carried out by inductively coupled plasma mass spectrometry (ICP-MS), and determination of amino acid composition by high-performance liquid chromatography (HPLC). The data obtained indicate that of the detected trace elements, K, Mg, Ca, Fe, Na, P and AI are contained in the largest amount, which is essential when creating a diuretic drug, and the concentrations of heavy metals and arsenic in the analyzed preparation did not exceed the regulated limit according to the requirements of WHO and GF XIV.