Annals and Essences of Dentistry
  • Year: 2010
  • Volume: 2
  • Issue: 4

Autoimmunity: Molecular Pathogenesis and Associated Oral Diseases

  • Author:
  • V Aparna1, Leela Krishna Mohan2
  • Total Page Count: 3
  • Page Number: 218 to 220

1Reader, Department of oral pathology, Drs Sudha & Nageswara Rao Siddhartha Institute of Dental Sciences, Chinnaoutpalli, Gannavaram, Vijayawada, Andhra Pradesh- 521286.

2Associates Professor, Department of Oral & Maxillofacial Surgery, Drs Sudha & Nageswara Rao Siddhartha Institute of Dental Sciences, Chinnaoutpalli, Gannavaram, Vijayawada, Andhra Pradesh- 521286.

Abstract

Autoimmunity can be defined as an immune response against self -antigens so called self-tolerance. The etiology is considered as multifactorial. Humoral or cellular immune mechanisms are responsible for various systemic and organ specific autoimmune diseases. Advances made in this field to know the immunopathology of autoimmune diseases affecting the oral tissues.

Keywords

Autoimmunity, Self-antigen, Self-tolerance, T- lymphocytes, B- lymphocytes