Annals and Essences of Dentistry

  • Year: 2011
  • Volume: 3
  • Issue: 4

Bisphosphonates: Can these be the bone eaters?

  • Author:
  • Ajay Chhabra1, Vandana Chhabra2
  • Total Page Count: 6
  • DOI:
  • Page Number: 94 to 99

1Professor and Head, Bhojia Dental College Baddi, H.P, India

2Senior Lecturer, SKSS Dental College, Ludhiana, Punjab, India

Abstract

Bisphosphonates are a group of synthetic analogs of inorganic pyrophosphate (an endogenous regulator of bone mineralization) Bisphosphonates are a family of drugs used to prevent and treat osteoporosis, multiple myeloma, Paget's disease (bone cancers), and bone metastasis from other cancers. These drugs can bond to bone surfaces and prevent osteoclasts (cells that breakdown bone) from doing their job.

Keywords

Bisphosphonates, BRONJ, osteonecrosis, BON