Acute Hemorrhagic Leukoencenpahalitis (AHL)

Acute hemorrhagic leukoencenpahalitis (AHL) was first described as pathological entity by thrust in 1941. It is a rare acute inflammatory myelinopathy of CNS characterized by progressive loss of consciousness leading to coma that usually results in death. AHL is thought to be a hyperacute form of acute disseminated encephatomylitis and diffuse hemorrhagic necrosis of CNS. AHL is known to be a immune reaction to some antigenic cross reactivity to myelin basic proteins and infection antigen usually following infection/vaccination. We report a rare case of AHL, developed after P. falciparum infection in an otherwise healthy 23 years old male.