Annals of Geriatric Education and Medical Sciences
Open Access
  • Year: 2014
  • Volume: 1
  • Issue: 2

An interesting case of Glanzmann Thromboasthenia

  • Author:
  • Shruti Bajad1,, Chetan Rijhwani2, Nisha Sehrawat3, Naval Mendiratta4
  • Total Page Count: 4
  • Page Number: 66 to 69

1Senior Resident, Medanta, Gurgaon

2Senior Resident, Internal Medicine Fortis, Delhi

3Senior Resident, Dept. of Pathology, DDU Hospital, Delhi

4Attending Consultant, Dept. of Rheumatology and Clinical Immunology, Medanta, Gurgaon

*Corresponding Author: E-mail: shrutibajad@yahoo.in

Online published on 19 June, 2015.

Abstract

Glanzmann's thrombasthenia (GT) was reported and described as a bleeding diathesis seen in children and characterized by diminished clot retraction. The disorder is caused by a deficiency in the platelet membrane glycoprotein IIb–IIIa complex, with bleeding due to defective platelet hemostatic plug formation. The recurrent features of GT include purpura, epistaxis, gingival hemorrhage and menorrhagia. GT being an autosomal recessive trait is reported to be especially prevalent in populations where intermarriage is common. Typically, the patients are diagnosed in infancy within the age of five. Though no differences appear to occur based on sex females more frequently present with bleeding. We report the case of a male patient with GT who presented with the chief complaint of gingival bleeding. The patient was given platelet transfusion followed by proper oral hygiene instructions. The report discusses management considerations for GT patients.

Keywords

Gingival Bleeding, Glanzmann Thrombasthenia, Young Male