*Corresponding Author : binuthomasct@gmail.com
As part of the Silk Road initiative, the introduction of numerous Chinese specialties, including silk, porcelain, and tea leaves, along with staples like millet, rice, sorghum, cinnamon, and spice ginger, to different parts of the world greatly aided in the advancement of civilizations. Among these, gingers occupied a significant position in Indian culture. For centuries, ginger (Zingiber officinale), a member of the Zingiberaceae family, has been valued not only as a culinary spice but also for its medicinal properties. People have long used ginger and its general compounds-Fe, Mg, Ca, vitamin C, flavonoids, phenolic compounds (gingerdiol, gingerol, gingerdione, and shogaols), sesquiterpenes, and paradols- as herbal remedies to treat a variety of symptoms, including pain, vomiting, and cold symptoms. It is also used for rheumatism, sore throats, arthritis, cramps, sprains, indigestion, vomiting, constipation, dyspepsia, hypertension, fever, and infectious infections. Studies have also demonstrated its wide range of therapeutic properties, including anti-inflammatory, anti-apoptotic, anti-tumor activities, anti-pyretic, anti-platelet, antitumourigenic, antihyperglycaemic, antioxidant, antidiabetic, anti-clotting and analgesic properties, as well as its cardiovascular and cytotoxic effects. The primary phytocompounds responsible for ginger’s pharmacological properties include 6-gingerol, 6-shogaol, and zingerone, in addition to other phenolics and flavonoids. Specific anti-inflammatory and antioxidant qualities are known to exist in gingerol and shogaol. The present review highlights the potential use of ginger in both traditional and modern medicine, with special emphasis on its introduction as a part of the Silk Road initiative and its importance in Indian culture.
Spices, Silk road, Ginger, Gingerol, Therapeutic effects