Characteristic features of morphological changes in the spleen tissue of white rats after a moderate traumatic brain injury

The experiments were carried out on 14 white mongrel rats of 3 months of age. Experimental animals were attached to a device made by hand in the form of a wheeled vehicle, these animals accelerated on the vehicle at a speed of 7 km/h and hit the wooden barrier with the frontal part of the head. All animals were kept in satisfactory conditions in the vivarium of the medical institute in compliance with the standards of care for laboratory animals. These laboratory rats, prior to injury, were trained in the Morris Water maze to determine the preservation of cognitive memory and the acquisition of skills for survival in water, which was evaluated by temporal and territorial indicators. The experiment was conducted on animals that received a moderate traumatic brain injury. Experimental rats after the experiment, after ether anesthesia by means of instant decapitation of animals were beheaded on the spot. Then the abdominal cavity was opened and the spleen was removed. After that, the spleen was examined and studied on the spot, as well as the necessary dimensions were measured in accordance with the established procedure.