Correction of disturbed parts of the immune system with thimoptinum in patients with chronic cholecystitis

Immune system was analyzed in 55 patients with Chronic Cholecystitis (CC) and 36 healthy individuals. Patients identified suppression of T-Systems and its subpopulations, voltage moral immunity. Traditional methods of treatment did not lead to the elimination of the immunodeficiency in patients with chronic cholecyctitis. Thymoptinum a total dose of 1.0 mg-1.2 mg (per course), applied in 21 patients with chronic cholecyctitis eliminated immune disorders, raised the entire spectrum of cell-mediated immunity, possessed immune correction and therapeutic effect. Disorders of the immune status, detected in chronic inflammatory diseases of the nutritional-rhenium, in a certain way influence the course of the disease, contribute to chronicity of inflammation-reducing process and eventually repair mechanisms. Evidently, increasing the amount concentration of IgG in patients is due to zone presence of antigens as a permanent "focus excitation" in these as relates to the IgG antibodies are actively functioning, with the direct participation of which agglutination and lysis of foreign agents [5–8, 10]. Introduction to the scheme of combined treatment of patients with CC Thymoptinum led to an increase in cellular and humoral immunity. Under the influence of Thymoptinum hap-pening efficiency increase initially reduced values of the immune system. Analysis of the clinical and immunological and laboratory instrumental research methods, depending on the used treatments pointed to favorable for pathologists-agency process in patients when applying immune correcting treatment. Thus, patients with CC has the following changes in their immunogram: decreasing CD3, CD4, CD8 cells; increasing in CD19; decrease levels of IgA and IgM; increase in IgG and CEC. Changes in the immune system suggest that patients had to identify immunodeficiency, especially on the part of the T-immunity. Apparently, immunodeficiency state by nature is secondary.