*Head of the Department of Pathology State Institution, Republican Specialized Scientific-Practical Medical Center of Oncology and Radiology of Uzbekistan, Dhd, Tashkent, Uzbekistan. Email id: dnishanov@mail.ru
**Head of the Department of Oncology with a course Of ultrasound diagnostics at the Tashkent Institute Of Advanced Medical Studies, Professor, Dhd, Tashkent, Uzbekistan. Email id: nkarimova87@yandex.ru
***Radiation oncologist Department of Radiotherapy Of State Institution Republican Specialized Scientific-Practical, Medical Center of Oncology and Radiology of Uzbekistan, Tashkent, Uzbekistan. Email id: nkarimova87@mail.ru
Online published on 17 August, 2019.
In biopsy preparations, there are 30 patients with cervical cancer at the IIb-IIIb clinical stages. A study in patients with locally advanced cervical cancer showed that a high expression level of Ki67 proliferation in primary patients, elevated levels of p53 protein before carrying out correlate with an unfavorable prognosis, which makes it possible to use these indicators in monitoring the course of the disease. It was shown that prior to the initiation of antitumor treatment, the expression level of Ki67 was as high as possible in those patients who subsequently showed progression of the disease, and reached 85%. The expression level of Ki67 and p53 protein was shown to correlate with indicators of tumor progression.
Locally Advanced Cervical Cancer, Ki67, Bcl2, P53
