Asian Journal of Multidimensional Research (AJMR)
  • Year: 2020
  • Volume: 9
  • Issue: 12

Treatment of hypercoagulable conditions in women with misscarriage in early gestation

Bukhara State Medical Institute, Bukhara, Uzbekistan

Online published on 12 February, 2021.

Abstract

The study involved 40 women with a history of recurrent early miscarriage. Laboratory criteria are: anti-cardiolipin antibodies IgG and / or IgM (on average or high titer 2 or more times in a row with an interval of 6 weeks); lupus anticoagulant (presence in plasma 2 or more times in a row with an interval of 6 weeks); beta2-glycoproteins-1. These patients were injected daily with LMWH subcutaneously in combination with aspirin at a daily dose of 100 mg and methylprednisolone at a daily dose of 4 mg under the control of a hemostasiogram (every two weeks). Perhaps this is due to the fact that all classic components of Virchow's triad are present even in uncomplicated pregnancy and childbirth.

Keywords

Anti-Cardiolipin, Hemostasiogram