Asian Journal of Pharmaceutical Analysis
  • Year: 2021
  • Volume: 11
  • Issue: 3

A Precise Review on Applications and Basic Concept of Direct Analysis in Real Time Mass Spectrometry (DART-MS)

  • Author:
  • Shivani Sharma, Navdeep Singh, Amar Deep Ankalgi, Arti Rana, Mahendra Singh Ashawat
  • Total Page Count: 9
  • Page Number: 243 to 251

Laureate Institute of Pharmacy, Kathog, Jawalamukhi, Himachal Pradesh- 176031, India

*Corresponding Author E-mail: navdeepsingh23.ns@gmail.com

Online published on 1 October, 2021.

Abstract

Direct real time analysis (DART) is the most successful tool for the analysis of the compounds. This technique is useful for the identification, and classification of compounds. It is widely followed by the forensic chemistry, and also used for many purposes. Their main applications include inks, paints, drugs, bank dyes, explosives, beverages, and gunshot etc. The basic concepts of DART-MS were highlighted to understand the process. Also the basic fundamentals of DART-MS including special function were discussed. Various natural products were discovered by DART-MS includes plant tissue, insects, and microbe etc. The main focus of this review article is on the applications of direct real time analysis, which covers the varieties of uses in our pharmaceutical as well as chemical industries. This technique was helpful in the production of food material, and to identify the contaminants from animal sources in the part of veterinary drugs. Also, used in food processing in the form of additives, and adulterants. DART-MS has huge applications on analysis of seized drug like steroids supplements, psychoactive plants etc. Also, in inks, paint, and documents industry this technique has been widely used. So, this review covers the basic fundamentals of direct real time analysis DART-MS, and their applications.

Keywords

DART-MS, Concept of direct analysis in real time, discovery of natural products, and applications