1Department of Quality Assurance, Shri D. D. Vispute College of Pharmacy and Research Center, Devad, Vichumbe, Gut No.104, Adjacent to Mumbai-Pune Express Highway, Tal. Panvel, Dist. Raigad, Maharashtra, India, 410 221
2Mini Drugs Testing LaboratoryOffice of the ADC (I), Central Drugs Standard Control Organization, M/s JWR Logistic Pvt Ltd 15-45, National Highway 4B, Panvel - JNPT Highway, Village Padeghar, Post - Vahal, Panvel - Maharashtra, India, 410206
3Department of Pharmacognosy and Phytochemistry, Shri D. D. Vispute College of Pharmacy and Research Center, Devad, Vichumbe, Gut No.104, Adjacent to Mumbai - Pune Express Highway, Tal. Panvel, Dist. Raigad, Maharashtra, India, 410 221
*Corresponding Author E-mail: priyawani703@gmail.com
Online published on 9 April, 2025.
UV spectrophotometry was performed by Lab India Analytical UV 3092 using methanol as medium. The resolution process was performed in the range of 200-400nm to determine the maximum absorption (λ max). The λmax of Nirmatrelvir was found to be 210nm. Measure the absorbance of 10, 20, 30, 40, 50, and 60μg/ml drug solution and measure the maximum absorbance at 210 nm with a blank control. Then draw a graph from the concentration on the X-axis and the absorbance on the Y-axis to get a straight line. Validation parameters such as linearity, precision, specificity, LOD and LOQ, accuracy and robustness were evaluated according to ICH guidelines.
Nirmatrelvir, UV, Bulk and In-house tablet formulation, Development, Validation
