Asian Journal of Pharmaceutical Analysis
  • Year: 2012
  • Volume: 2
  • Issue: 4

A New Analytical Method Development and Validation for Estimation of Ciprofloxacin in Bulk and Pharmaceutical Dosage Form

  • Author:
  • Manoranjan Sabat1,, Sharada Nalla1, Venkateswarlu Goli1, Sravan Prasad Macherla2, Praveena Kumari Matta2, S. Madhu Chandaka2
  • Total Page Count: 2
  • Page Number: 116 to 117

1Venkateswara Institute of Pharmaceutical Seinces, Cherlapally, Nalgonda -508001

2Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist. -501510

*Corresponding Author E-mail: sabatmanupharma10@gmail.com

Online published on 19 June, 2014.

Abstract

A sensitive, precise, accurate and simple UV spectrophotometric method has been developed for estimation of ciprofloxacin in bulk and pharmaceutical dosage form. The drug shows maximum absorbance at 273 nm (λmax). The linearity was observed in the concentration range of 5-50mcg/ml. The proposed method has been applied successfully to the analysis of cited drug in pharmaceutical formulation. Recovery study was performed to confirm the accuracy of the method. The method was validated as per ICH guide lines.

Keywords

Estimation, Ciprofloxacin, UV Spectrophotometer