Asian Journal of Pharmaceutical Analysis
  • Year: 2013
  • Volume: 3
  • Issue: 2

Development and validation of a Spectrophometric method for estimation of Triamcinolone in solid dosage form

  • Author:
  • Shiv Kumar Gupta1,, Babita Kumar1, Pramod Kumar Sharma2
  • Total Page Count: 2
  • Page Number: 42 to 43

1College of Pharmacy, Shree Ganpati Institute of Technology, NH-24, Opp. Jindal Pipes Ltd, Ghaziabad, (U.P.) India

2School of Pharmacy, Galghotia University, Greater Noida, G B Nagar, (U. P.) India

*Corresponding Author E-mail: shiv.gupta@sgit.ac.in

Online published on 19 June, 2014.

Abstract

The new simple, sensitive, accurate, precise, rapid and economical method was developed for the estimation of Triamicinolone in solid dosage form. Method is based on the absorbance. Triamcinolone maximum is found at 238 nm in methanol water solvent. The linearity was obtained in the concentration range of 3–9 mcg/ml with coefficient of correlation 0.9998. The value of ruggedness and robustness was found to be 0.2182 and 0.43 respectively. The method is found to be accurate, precise and useful in quality control of dosage form.

Keywords

Triamcinolone, Spectrophotometric, Validation