Asian Journal of Pharmaceutical Analysis
  • Year: 2014
  • Volume: 4
  • Issue: 1

Investigation of antibacterial and haemolytic activity of Russell's viper and Echis carinatus venom

  • Author:
  • AK. Prabhakaran1,, P. Kumaravel1, J. Priya1, G. Melchias2, A. Edward3, G. Sridevi4
  • Total Page Count: 4
  • Page Number: 1 to 4

1Department of Biotechnology, Vysya College, Salem-636 103, Tamil Nadu, India

2Department of Botany, St. Joseph's College (Autonomous), Tiruchirappalli-620 002, Tamil Nadu, India

3Department of Biotechnology, St. Joseph's College (Autonomous), Tiruchirappalli-620 002, Tamil Nadu, India

4Department of Antitoxin, King's Institute of Preventive Medicine and Research, Guindy, Chennai-600 032, Tamil Nadu, India

*Corresponding Author E-mail: prabhabiotech@gmail.com

Online published on 19 June, 2014.

Abstract

Snake bites represent a serious public health problem around the world. Snake venom known to cause different metabolic disorders by altering the cellular and enzymatic activities in animals. The present study aims to investigate the effect of antibacterial and haemolytic activity of Russell's viper (RV) and Echis carinatus (EC) venom. Most bacteria's are highly active against RV and EC venom at this concentration (100μg/ml). The current results showed that Russell's viper and Echis carinatus venom has a significant antibacterial effect against Escherichia coli, Pseudomonas aeruginosa and Vibrio cholera by comparing with standard antibiotics. The haemolytic activity effect was determined with blood agar plates and finally it confirms the venom having a property of haemolysis.

Keywords

Russell's viper, Echis carinatus, Antibacterial activity, Haemolytic activity