Asian Journal of Pharmaceutical Analysis
  • Year: 2014
  • Volume: 4
  • Issue: 4

Synthesis, Characterization and antimicrobial activity of Co(II), Ni(II), Cu(II) and Zn(II) complexes N-O-S donor ligands

  • Author:
  • Vinita Gupta1, Sanchita Singh1, Y.K. Gupta2,
  • Total Page Count: 4
  • Page Number: 174 to 177

1Department of Chemistry, Agra College, Agra, U.P., India

2Head Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, India

*Corresponding Author E-mail: ykgbkbiet@rediffmail.com, ykgbkbiet123@gmail.com

Online published on 5 February, 2015.

Abstract

The Co(II), Ni(II), Cu(II) and Zn(II) complexes of the composition 1:1:1 molar ratio, (ML1L2) (where L1=diphenylamine-2-mercapto-2-carboxylic acid and L2=2-furyl glyoxalanthranilic acid have been synthesized and characterized by elemental analyses, 1H-NMR, IR, electronic spectral data and magnetic susceptibility measurements. The synthesized ligands and their metal complexes were screened for their antimicrobial activity against two bacteria Staphylococcus aureus (gram +ve) and Escherichia coli (gram -ve) and two fungi Aspergillus niger and Apergillus flavus by Serial Dilution Method. Metal complexes are more active than their ligands.

Keywords

Mixed ligand complexes, Antimicrobial Activity