A Review on Analytical Techniques for Estimation of Anti Cholinergic Drug: Glycopyrronium Bromide

Glycopyrronium bromide is a Anticholinergic class of drug indicated for the treatment of chronic obstructive pulmonary drug. Various analytical methods used for the estimation of Glycopyrronium bromide has been reviewed in this paper. These include Ultraviolet spectrometry, High performance thin layer chromatography, High performance liquid chromatography, Ion pair, to determine the amount of Glycopyrronium bromide in bulk drugs and pharmaceutical formulations and Biological Fluids. Stability indicating and impurity profiling methods for Glycopyrronium bromide are also described. These analytical methods can be used for qualitative and quantitative estimation of Glycopyrronium bromide and/or its related impurities or degradants in bulk and formulation.