Asian Journal of Pharmaceutical Research

  • Year: 2011
  • Volume: 1
  • Issue: 4

Antibacterial Activity of Cardiospermum halicacabum and Melothria heterophylla

  • Author:
  • M. Mariyappan1, R. Bharathidasan1, R. Mahalingam1, P. Madhanraj2, A. Panneerselvam1, V. Ambikapathy1,
  • Total Page Count: 3
  • DOI:
  • Page Number: 111 to 113

1P.G. Research, Dept. of Botany and Microbiology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi – 613503, Thanjavur. DT, Tamil Nadu, India

2Dept of Microbiology, Thanthai Hans Roever College of Arts and Science, Perambalur -621 212, Tamil Nadu, India

Abstract

The bacterial organisms were isolated from drinking water (Bacillus, Borchothrix, Clavibacter sp, Ancylobacter sp, and Brevi bacterium). Selected Indian medicinal plants Cardiospermum halicacabum and Melothria heterophylla were selected for antibacterial studies. The solvents used for the extraction of plant roots were n-butanol, ethyl acetate and distilled water. The invitro antibacterial activity was performed by agar well diffusion method. The most susceptible Gram-Postive bacteria was Bacillus sp, Brevibacterium sp, and the most susceptible Gram-negative bacteria was Borchothrix sp, Clavibacter sp, and Ancylobacter sp. The extracts of plant Cardiospermum halicacabum and Melothria heterophylla inhibited the growth of the bacterial strains investigated. The most active extracts was compared with the standard antibiotics, penicillin, Streptomycin and Ampicillin 100mg/disc). The results obtained in the present study suggest that Cardiospermum halicacabum and Melothria heterophylla could be used in treating diseases caused by the test organisms. The results are discussed in detail.

Keywords

Medicinal Plants, antibacterial activity, aqueous extract, n-butanol excretory ethyalcetate extract