Asian Journal of Pharmaceutical Research
  • Year: 2020
  • Volume: 10
  • Issue: 2

Formulation and Evaluation of Bioadhesive Buccal Drug Delivery of Sumatriptan Succinate Tablets

Department of Pharmaceutics, Nalanda College of Pharmacy, Jawaharlal Nehru Technological University, Hyderabad, Telangana

*Corresponding Author E-mail: rajinisuralabs1@gmail.com

Online published on 3 June, 2020.

Abstract

The objective of this study was to develop effective buccal tablets of Sumatriptan Succinate. Tablets of Sumatriptan Succinate were prepared by direct compression method using bioadhesive polymers like Poloxamer188, β-CD, HPMC K4M. Buccal tablets were prepared by taking polymers in different ratios. The formulation F9 showed maximum drug release (98.92%) in 8 hrs. It was considered as optimized formulation.

Keywords

Sumatriptan Succinate, Buccal tablets, Poloxamer188, β-CD, HPMC K4M, in-vitro drug release