Asian Journal of Pharmaceutical Research
  • Year: 2024
  • Volume: 14
  • Issue: 1

Pyranopyrimidine: A promising scaffold with various biological activities

Department of Pharmaceutical Chemistry, KMCH College of Pharmacy, Kovai Estate, Kalapatti Main Road, Coimbatore, Tamil Nadu - 641048

*Corresponding Author E-mail: sathyapooja2015@gmail.com

**banupharma76@gmail.com

Online published on 3 May, 2024.

Abstract

Heterocyclic compounds are one of the most important molecules in the synthesis of pharmacologically active compounds. One of the most promising heterocycles among all is the pyranopyrimidine scaffold, that has been found in both natural and synthetic sources. It has been confirmed to possess a range of biological activity, including anti-HIV, anti-tubercular, anti-HBV, anti-dyslipidemic, anti-platelet, anti-inflammatory, antioxidant, and antibacterial properties. The objective of this review is to highlight significant pyranopyrimidine analogues with a range of biological activity.

Keywords

Pyranopyrimidine, Antimicrobial activity, Docking, Staphylococcus aureus, Klebsiella pneumonia and Bacilluscereus