Biodegradable Polymers in Drug Delivery: A Detailed Review

Biodegradable polymers are crucial in drug delivery, providing notable benefits over traditional systems by degrading into non-toxic byproducts, ensuring biocompatibility, and eliminating the need for surgical removal. This review examines the fundamental principles, types, and synthesis methods of these polymers, alongside their degradation mechanisms in biological environments. The advantages, such as controlled release, enhanced bioavailability, and improved patient compliance, are discussed, as well as challenges like variability in degradation rates and potential immune responses. Recent advancements demonstrate significant improvements in polymer performance and applications, from oral and injectable systems to implantable devices and tissue engineering. Future research directions emphasize the potential for biodegradable polymers to revolutionize drug delivery, improving therapeutic efficacy and patient outcomes. This comprehensive review underscores the transformative impact of biodegradable polymers, highlighting.