A Mini Review on Drug Resistance among Bacterial Pathogens: Need for Novel Antibacterials

The natural phenomenon known as "antimicrobial resistance" occurs when bacteria become resistant to medications that originally worked to treat infections caused by these microbes. Associated with high rates of morbidity and mortality, medication resistance in bacterial pathogens is a global concern. Illnesses that are difficult to treat or even incurable with conventional antimicrobials have been linked to multidrug-resistant gram +ve and gram ve bacteria. Lack of early identification of pathogenic bacteria and their patterns of antimicrobial vulnerability in patients with bacteremia and other serious disorders leads to the widespread and frequently inappropriate administration of broad-spectrum antibiotics in healthcare settings. This mini-review summarizes the mechanisms by which bacteria develop drug resistance and focuses mostly on several forms of microbial drug resistance.