SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya, Bilaspur (CG) 495 007
*Corresponding Author E-mail: ah_bharti@yahoo.com
Online published on 18 June, 2014.
Bioavailability was assessed by determining the maximum (peak) plasma drug concentration of kankasava. Blank plasma gave no interfering peak at the retention time of piperine making the analysis very simple. In the plasma concentration – time profile of kankasava formulation in rats (n=6) piperine could be detected in plasma from 0.5 to 8 hours after administration with maximum plasma concentration (2.80 – 1.76 μg/ml) at 0.5 – 1 h post dosing.
