Asian Journal of Pharmacy and Technology

The learn of Sphaeranthus amaranthoides Burn, were examined for their antioxidant, antimutagenic, antimicrobial and phytochemical activities. Preliminary evaluation of both crude and solvent fractions showed a broad spectrum of activity since the extracts inhibit the growth of both bacterial and fungal isolates. The inhibitory activity of plant extracts on the peroxidation of linolic acid were measured by fericthiocynate methodo. Ethonolic extract showed strong antioxidant activity and antimicrobial activity against to the bacteria, (K.pneumoniae, S. typhi, E.coli, P.aeroginosa, S.aureus) and fungus (A.nidulans, A.terreus, A.sulphureus, Candida albicans and Fusarium sp.) cultures. Due to the phytochemical diversity in the antioxidant phytocompounds, the above results were expected. It almost rich in carotenes, Neoxanthin, chlorophyll a and chlorophyll b, lutein, violexanthin, pheophytin, which may have been responsible for the antioxidant, antimicrobial and for phytochemical activity. For antimutagenic activity using sodium azide to induce the chemical compound of Sphaeranthus amaranthoides Burn, to prevent the degenerative cells and results further support the view that some Indian medicinal plants are source for potential antioxidants.