Asian Journal of Pharmacy and Technology

Synthetic medicines developed are popular even among younger generations. The coumarine derivative drugs claim efficient cure of various disorders. Recently, coumarine compound analogues and their derivatives have attracted strong interest in medicinal chemistry due to their biological and pharmacological properties. The structure have offered a high value of diversity that is proven useful for the development of new medicinal drugs and improved potency, less toxicity and good pharmacological activity. The synthesized compounds were screened for their in-vitro growth inhibiting activity against different strains of bacteria Staphylococcus aureus and Escherichia coli at 50, 100, 150 and200 μg/ml concentrations by using agar well diffusion technique. The results were compared with the standard antibiotics Ciprofloxacin (100 μg/ml). The newly synthesized compound produced significant action against the bacterial strains at 100 μg/ml concentration.