Formulation and evaluation of ketoprofen emulgel for topical drug delivery system

Emulgel have emerged as an auspicious drug delivery system for the delivery of hydrophobic drugs. The impartial of the study was to prepare emulgel of ketoprofen, a non-steroidal anti-inflammatory drug, using Carbopol 940 as a gelling agent. Mentha oil and clove oil were used as diffusion enhancers. The emulsion was prepared and it was combined in a gel base. The formulations were evaluated for spreading coefficient studies, rheological studies, and ex vivo release studies. Formulations F2 and F3 show maximum release. So, it can be concluded that topical emulgel of ketoprofen possesses an effective anti-inflammatory and analgesic activity.