Asian Journal of Pharmacy and Technology

  • Year: 2024
  • Volume: 14
  • Issue: 4

Desmosomal cadherins: Specialized cells for adhesion property

1Department of Pharmaceutics, CMR College of Pharmacy, Affiliated to JNTUH, Medchal, Kandlakoya, Hyderabad - 501401, Telangana, India

2Professor and Principal, CMR College of Pharmacy, Medchal, Kandlakoya, Hyderabad, Telangana, India

Abstract

Adhesion is a phenomenon which is required to promote controlled release of the drug used in pronged therapies. In view of it, desmosomes are the specialized cells which connect cell to cell and thereby it forms tight junctions to promote diffusion of the drug. These desmosomal cadherins are majorly used in drug delivery to the skin, nasal delivery, buccal delivery and ophthalmic delivery where adhesion is required to provide long term therapy. The current review has been informed a mini review on the invention, morphological structure, functions and few applications of desmosomes.

Keywords

Adhesion, Desmosomes, Drug Delivery, Stratum Corneum