1Department of Pharmaceutics, CMR College of Pharmacy, Affiliated to JNTUH, Medchal, Kandlakoya, Hyderabad - 501401, Telangana, India
2Professor and Principal, CMR College of Pharmacy, Medchal, Kandlakoya, Hyderabad, Telangana, India
Adhesion is a phenomenon which is required to promote controlled release of the drug used in pronged therapies. In view of it, desmosomes are the specialized cells which connect cell to cell and thereby it forms tight junctions to promote diffusion of the drug. These desmosomal cadherins are majorly used in drug delivery to the skin, nasal delivery, buccal delivery and ophthalmic delivery where adhesion is required to provide long term therapy. The current review has been informed a mini review on the invention, morphological structure, functions and few applications of desmosomes.
Adhesion, Desmosomes, Drug Delivery, Stratum Corneum