Asian Journal of Pharmacy and Technology

The trend of seeking natural alternatives has triggered the invention of new products known as nutraceuticals which are health-beneficial and have an added value to basic nutrition. Multiple medicinal herbal formulations have brought their synergistic effect to the forefront and enhanced single medicinal therapy’s therapeutic potential. This study is concerned with forming and characterizing polyherbal granules as a carrier system for nutraceuticals. The polyherbal granules were prepared using extracts from several plants with antioxidant, anti-inflammatory, and immunomodulatory properties. The granules were designed and prepared to facilitate oral administration, controlled release, and increased bioavailability of the active ingredients. This included identification of the appropriate herbs, extraction of their bioactive components using suitable solvents, and standardization of the preparation of the granules with regard to granulation, drying, and sieving processes. Various physical parameters such as particle size, flow ability, and compressibility were assessed in addition to the kinetics of in vitro release studies of the nutraceuticals incorporated into the granules. The granule formulation was evaluated for its stability under different storage parameters to provide assurance on its effectiveness for a longer period. The preparation of the polyherbal nutraceutical granule has shown good and favourable results within the time period of the study regarding the components used.